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parameters.m
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executable file
·27 lines (27 loc) · 1.02 KB
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function [M, N, rerun, type, plottype, MWreceptor, MWligand, LinkerNLig, UnitDiameterLig, LinkerNRec,...
UnitDiameterRec, Kon, Koff, Kon2, Koff2, Kon3, Koff3, Kon4, Koff4, OnTime, OffTime, KMTL, L0, baseRU] = parameters
M = 2;
N = 2;
rerun = 1;
type = 1;
plottype = 1; %plottype =1 will calculate
MWreceptor = 865.94 + 807.9;%736.82 + 833.85;%865.94 + 807.9; %average of both pTyr binding motifs
MWligand = 11587.07+11764.29;%11587.07+11764.29;%10352.9 + 10704.32;10594.2+10736.19 %average diameter of SH2 domains in PTPN11
LinkerNLig = 5.75;
UnitDiameterLig = 36;%35
LinkerNRec = 31;%10; %31
UnitDiameterRec = 19;
Kon = 50000;%251889.169;
Koff = 1; %1
Kon2 = 1;
Koff2 = 1; %1
Kon3 = 1;%1907013.997;
Koff3 = 1; %1
Kon4 = 5000000;%426712.182;
Koff4 = 1; %1
OnTime = 30; %500;
OffTime = 30; %500
KMTL = 1;
L0 = .25e-6; %4e-6 %1e-6 %initial Ligand concentration. This value should be higher than the expected affinity in a sweep
baseRU = 25; %25
end