diff --git a/internal/adc/translator/httproute.go b/internal/adc/translator/httproute.go
index 4acabd31..fb6cf707 100644
--- a/internal/adc/translator/httproute.go
+++ b/internal/adc/translator/httproute.go
@@ -741,6 +741,10 @@ func (t *Translator) translateGatewayHTTPRouteMatch(match *gatewayv1.HTTPRouteMa
 			})
 
 			route.Vars = append(route.Vars, this)
+			// APISIX Admin API requires uris to be a non-null array. Use "/*"
+			// as a catch-all so APISIX accepts the route; the vars entry above
+			// performs the actual regex filtering.
+			route.Uris = []string{"/*"}
 		default:
 			return nil, errors.New("unknown path match type " + string(*match.Path.Type))
 		}
diff --git a/test/e2e/gatewayapi/httproute.go b/test/e2e/gatewayapi/httproute.go
index 75197a29..e9432002 100644
--- a/test/e2e/gatewayapi/httproute.go
+++ b/test/e2e/gatewayapi/httproute.go
@@ -942,6 +942,60 @@ spec:
 			})
 		})
 
+		It("HTTPRoute RegularExpression Match", func() {
+			var regexRoute = fmt.Sprintf(`
+apiVersion: gateway.networking.k8s.io/v1
+kind: HTTPRoute
+metadata:
+  name: httpbin
+spec:
+  parentRefs:
+  - name: %s
+  hostnames:
+  - httpbin.example
+  rules:
+  - matches:
+    - path:
+        type: RegularExpression
+        value: /status/[0-9]+
+    backendRefs:
+    - name: httpbin-service-e2e-test
+      port: 80
+`, s.Namespace())
+
+			By("create HTTPRoute with RegularExpression path type")
+			s.ResourceApplied("HTTPRoute", "httpbin", regexRoute, 1)
+
+			By("access dataplane: path matching regex should succeed")
+			s.RequestAssert(&scaffold.RequestAssert{
+				Method:   "GET",
+				Path:     "/status/200",
+				Host:     "httpbin.example",
+				Check:    scaffold.WithExpectedStatus(http.StatusOK),
+				Timeout:  time.Second * 30,
+				Interval: time.Second * 2,
+			})
+
+			s.RequestAssert(&scaffold.RequestAssert{
+				Method:   "GET",
+				Path:     "/status/201",
+				Host:     "httpbin.example",
+				Check:    scaffold.WithExpectedStatus(http.StatusCreated),
+				Timeout:  time.Second * 30,
+				Interval: time.Second * 2,
+			})
+
+			By("access dataplane: path not matching regex should return 404")
+			s.RequestAssert(&scaffold.RequestAssert{
+				Method:   "GET",
+				Path:     "/status/ok",
+				Host:     "httpbin.example",
+				Check:    scaffold.WithExpectedStatus(http.StatusNotFound),
+				Timeout:  time.Second * 30,
+				Interval: time.Second * 2,
+			})
+		})
+
 		It("HTTPRoute Method Match", func() {
 			By("create HTTPRoute")
 			s.ResourceApplied("HTTPRoute", "httpbin", fmt.Sprintf(methodRouteGETAndDELETEByAnything, s.Namespace()), 1)