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  • This repo contains input files for evaluating the GAFF2/ABCG2 model in hydration free energy (HFE) and protein-ligand relative binding free energy (RBFE) calculations published in this PAPER.
  • ./Hydration_dG contains the input files and dG results of HFE calculations.
  • ./RBFE contains the input files and results of RBFE calculations.
  • All the dg and ddg estimates are in kcal/mol.