diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index 3b2cda04cf6..c5ea4cd863e 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -519,6 +519,10 @@ jobs:
         shell: bash
         run: |
           choco install visualstudio2022buildtools --package-parameters "--add Microsoft.VisualStudio.Workload.VCTools --includeRecommended --passive" -y
+      - name: Install LLVM / Clang (Windows)
+        if: matrix.os == 'windows-x64'
+        shell: bash
+        run: choco install llvm -y
       - name: Setup Python (Windows)
         if: matrix.os == 'windows-x64'
         uses: actions/setup-python@v5
@@ -533,7 +537,7 @@ jobs:
           tool: nextest
       - name: Rust Tests (Windows)
         if: matrix.os == 'windows-x64'
-        run: cargo nextest run --locked --workspace --all-features --no-fail-fast --exclude bench-vortex --exclude vortex-python --exclude vortex-duckdb --exclude vortex-fuzz
+        run: cargo nextest run --locked --workspace --all-features --no-fail-fast --exclude bench-vortex --exclude vortex-python --exclude vortex-fuzz
       - name: Rust Tests (Other)
         if: matrix.os != 'windows-x64'
         run: cargo nextest run --locked --workspace --all-features --no-fail-fast --exclude bench-vortex --exclude vortex-duckdb
diff --git a/vortex-duckdb/build.rs b/vortex-duckdb/build.rs
index e9b484f8f24..dfa25d3f548 100644
--- a/vortex-duckdb/build.rs
+++ b/vortex-duckdb/build.rs
@@ -36,6 +36,8 @@ fn download_duckdb_lib_archive() -> Result<PathBuf, Box<dyn std::error::Error>>
         "x86_64-apple-darwin" => ("osx", "universal"),
         "x86_64-unknown-linux-gnu" => ("linux", "amd64"),
         "aarch64-unknown-linux-gnu" => ("linux", "arm64"),
+        "x86_64-pc-windows-msvc" => ("windows", "amd64"),
+        "aarch64-pc-windows-msvc" => ("windows", "arm64"),
         _ => return Err(format!("Unsupported target: {target}").into()),
     };
 
@@ -71,9 +73,11 @@ fn extract_duckdb_libraries(archive_path: PathBuf) -> Result<PathBuf, Box<dyn st
         .ok_or("Invalid archive path")?
         .to_path_buf();
 
-    // Check if already extracted. The archive for Linux only contains a .so library, macOS only .dylib.
+    // Check if already extracted. The archive for Linux contains
+    // a .so library, macOS .dylib and Windows a .dll file.
     if duckdb_lib_dir.join("libduckdb.dylib").exists()
         || duckdb_lib_dir.join("libduckdb.so").exists()
+        || duckdb_lib_dir.join("duckdb.dll").exists()
     {
         println!("DuckDB libraries already extracted, skipping extraction");
         return Ok(duckdb_lib_dir);
@@ -204,7 +208,7 @@ fn build_duckdb(duckdb_source_root: &Path) -> Result<PathBuf, Box<dyn std::error
     }
     fs::create_dir_all(&duckdb_library_dir)?;
 
-    // Copy .dylib and .so files (macOS and Linux).
+    // Copy .dylib, .so, and .dll files (macOS, Linux, and Windows).
     for entry in fs::read_dir(build_dir.join("src"))? {
         let entry = entry?;
         let path = entry.path();
@@ -233,8 +237,13 @@ fn main() {
     let zip_source_path = download_duckdb_source_archive().unwrap();
     let extracted_source_path = extract_duckdb_source(zip_source_path).unwrap();
     drop(fs::remove_dir_all(&duckdb_repo));
+
+    #[cfg(unix)]
     std::os::unix::fs::symlink(&extracted_source_path, &duckdb_repo).unwrap();
 
+    #[cfg(windows)]
+    std::os::windows::fs::symlink_dir(&extracted_source_path, &duckdb_repo).unwrap();
+
     let library_path =
         // DuckDB debug build is linked in case of `VX_DUCKDB_DEBUG=1`.
         if env::var("VX_DUCKDB_DEBUG").is_ok_and(|v| matches!(v.as_str(), "1" | "true")) {
@@ -293,23 +302,37 @@ fn main() {
     println!("cargo:rerun-if-env-changed=VX_DUCKDB_SAN");
     println!("cargo:rustc-link-search=native={}", library_path.display());
     println!("cargo:rustc-link-lib=dylib=duckdb");
+
+    #[cfg(unix)]
     println!("cargo:rustc-link-arg=-Wl,-rpath,{}", library_path.display());
 
     // Compile our C++ code that exposes additional DuckDB functionality.
-    cc::Build::new()
-        .std("c++17")
-        // Enable compiler warnings.
-        .flag("-Wall")
-        .flag("-Wextra")
-        .flag("-Wpedantic")
-        // Allow C++20 designator syntax even with C++17 std
-        .flag("-Wno-c++20-designator")
-        // Enable C++20 extensions
-        .flag("-Wno-c++20-extensions")
-        // Unused parameter warnings are disabled as we include DuckDB
-        // headers with implementations that have unused parameters.
-        .flag("-Wno-unused-parameter")
-        .cpp(true)
+    let mut builder = cc::Build::new();
+    builder.std("c++17").cpp(true);
+
+    #[cfg(target_os = "windows")]
+    {
+        builder
+            // Enable C++ exception handling
+            .flag("/EHsc");
+    }
+
+    #[cfg(not(target_os = "windows"))]
+    {
+        builder
+            .flag("-Wall")
+            .flag("-Wextra")
+            .flag("-Wpedantic")
+            // Allow C++20 designator syntax even with C++17 std
+            .flag("-Wno-c++20-designator")
+            // Enable C++20 extensions
+            .flag("-Wno-c++20-extensions")
+            // Unused parameter warnings are disabled as we include DuckDB
+            // headers with implementations that have unused parameters.
+            .flag("-Wno-unused-parameter");
+    }
+
+    builder
         // We include DuckDB headers from the DuckDB extension submodule.
         .include(duckdb_repo.join(format!("duckdb-{}/src/include", DUCKDB_VERSION.as_str())))
         .include("cpp/include")