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ChromHandler - handling time-resolved chromatographic data

PyPI - Version Documentation

ℹ️ Overview

chromhandler is Python software that streamlines data acquisition and processing for chromatographic time-course reaction data.

It is built to reduce manual spreadsheet work and to support reproducible processing workflows from exported chromatograms to structured, analysis-ready datasets. The package focuses on handling chromatographic measurements, organizing metadata, aggregating peaks of interest, and preparing consistent outputs for downstream analysis.

🚀 Upcoming release

A new version planned for 04/2026 will introduce:

  • 📊 Joint analysis of chromatographic time-course data
    Improved support for processing related chromatograms as coherent experimental series.

  • 🧩 Streamlined creation of analysis-ready datasets
    Faster transition from exported chromatograms to structured datasets ready for downstream evaluation.

  • 🎲 Probabilistic peak processing
    Support for uncertainty-aware peak handling and more robust area estimation.

⭐ Key features

  • 🌱 Low-friction chromatogram processing
    Process exported chromatographic data without relying on spreadsheet-based workflows.

  • 🧪 Metadata enrichment
    Attach reaction metadata such as time, temperature, pH, or sample information to chromatographic measurements.

  • 📈 Calibration support
    Create and apply calibration curves for consistent concentration estimation across experiments.

  • ⏱️ Time-course data handling
    Organize chromatographic reaction series in a structured and reproducible way.

  • 📂 FAIR-oriented outputs
    Prepare datasets for transparent reuse and downstream integration.

🛠️ Installation

Install from PyPI:

pip install chromhandler

About

🌈 chromhandler is a Python package designed to streamline the processing and analysis of chromatographic data, enabling efficient metadata enrichment and conversion to EnzymeML format for further analysis.

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