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feat: add example ebolavirus mutation pattern configs#456

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feat/mutation-pattern-analysis
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feat: add example ebolavirus mutation pattern configs#456
ivan-aksamentov wants to merge 1 commit into
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feat/mutation-pattern-analysis

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@ivan-aksamentov ivan-aksamentov commented May 26, 2026

Placeholder mutationPatterns configuration for all three Orthoebolavirus species to demonstrate the feature

⚠️ event filters, clustering parameters, and motifs are not scientifically validated

Work items

  • Add mutationPatterns config to BDBV (ADAR + APOBEC), EBOV (ADAR + APOBEC CpG), and SUDV (ADAR-only) pathogen.json files with species-specific clustering parameters
  • Add synthetic ADAR-dense and APOBEC-dense example sequences to BDBV
  • Add changelog entries and rebuild unreleased dataset artifacts

Placeholder mutationPatterns configuration for BDBV, EBOV, and SUDV to demonstrate the feature; parameters are not scientifically validated.

- BDBV: ADAR (A>G, T>C) and APOBEC (G>A in YGH context), window 50, cutoff 3, with synthetic example sequences
- EBOV: ADAR (A>G, T>C) and APOBEC-like CpG deamination (C>T in HCG context), window 100, cutoff 5
- SUDV: ADAR (A>G, T>C), window 80, cutoff 4
@ivan-aksamentov ivan-aksamentov deployed to refs/pull/456/merge May 26, 2026 10:14 — with GitHub Actions Active
@ivan-aksamentov ivan-aksamentov marked this pull request as draft May 26, 2026 10:14
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