Fixes #3640 Update eyelid textual definition

[aleixpuigb]

Fixes #3640
The eyelid is a composite anatomical structure that is not solely composed by skin. This PR updates the definition to reflect this and provides a dbxref:

A movable anterior covering of the eye composed of skin, muscle, dense connective tissue (tarsal plate) with embedded meibomian glands, and palpebral conjunctiva; functions to protect the eyeball, distribute the tear film, and maintain the eyelash margin. (PMID:29493929)

[aleixpuigb]

#gogoeditdiff

[Copilot]

Pull request overview

This PR attempts to fix issue #3640 by reclassifying the eyelid from "organ part" to "zone of skin". However, this change is semantically incorrect based on the anatomical composition of the eyelid and established ontology patterns.

Key Changes:

• Changed the parent classification of eyelid (UBERON:0001711) from "organ part" (UBERON:0000064) to "zone of skin" (UBERON:0000014)

[Copilot]

This reclassification of eyelid as "zone of skin" is semantically incorrect. The eyelid is a complex multi-tissue structure, not just skin.

Evidence from the ontology itself:

1. Line 28989 documents that eyelid consists of 7 distinct layers: skin, subcutaneous connective tissue, striated muscle, submuscular connective tissue, fibrous layer, smooth muscle, and palpebral conjunctiva
2. Line 28986 notes that "FMA divides this into skin, fascia, conjunctiva"
3. The ontology already has a separate term "skin of eyelid" (UBERON:0001457) that is correctly classified as a "zone of skin"
4. Parts of the eyelid include levator palpebrae superioris (muscle, line 25855) and palpebral conjunctiva (mucous membrane, line 32063)

The correct pattern is established by "prepuce" (UBERON:0011374), which is also a "fold of skin and mucous membrane":

• Prepuce is classified as "external soft tissue zone", not "zone of skin"
• It has "has_part" relationships to both skin and mucosa
• Line 146065 includes a curator note: "this structure is a combination of skin and other tissue"

The eyelid should remain classified as "organ part" (UBERON:0000064) or be reclassified to something like "external soft tissue zone", with a "has_part" relationship to skin, rather than being classified directly as "zone of skin".

[Copilot]

Pull request overview

Copilot reviewed 1 out of 1 changed files in this pull request and generated no new comments.